Skeletal muscle dysfunction in COPD: relevance of nutritional support and pulmonary rehabilitation
نویسندگان
چکیده
منابع مشابه
Exercise and muscle dysfunction in COPD: implications for pulmonary rehabilitation.
Skeletal muscle dysfunction in COPD (chronic obstructive pulmonary disease) patients, particularly of the quadriceps, is of clinical interest because it not only influences the symptoms that limit exercise, but may also contribute directly to poor exercise performance and health status, increased healthcare utilization, and mortality. Furthermore, unlike the largely irreversible impairment of t...
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Hussain SN, Sandri M. Role of autophagy in COPD skeletal muscle dysfunction. J Appl Physiol 114: 1273–1281, 2013. First published October 18, 2012; doi:10.1152/japplphysiol.00893.2012.—Chronic obstructive pulmonary disease (COPD) is a debilitating disease caused by parenchymal damage and irreversible airflow limitation. In addition to lung dysfunction, patients with COPD develop weight loss, ma...
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Maltais, François, Jean Jobin, Martin J. Sullivan, Sarah Bernard, François Whittom, Kieran J. Killian, Marc Desmeules, Marthe Bélanger, and Pierre LeBlanc. Metabolic and hemodynamic responses of lower limb during exercise in patients with COPD. J. Appl. Physiol. 84(5): 1573–1580, 1998.—Premature lactic acidosis during exercise in patients with chronic obstructive pulmonary disease (COPD) may pl...
متن کاملSkeletal muscle dysfunction in COPD: clinical and laboratory observations.
COPD (chronic obstructive pulmonary disease), although primarily a disease of the lungs, exhibits secondary systemic manifestations. The skeletal muscles are of particular interest because their function (or dysfunction) not only influences the symptoms that limit exercise, but may contribute directly to poor exercise performance. Furthermore, skeletal muscle weakness is of great clinical impor...
متن کاملMicroRNAs and Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease (COPD)
COPD is defined by its effects on the lung, however skeletal muscle atrophy and a slow-to-fast fibre shift are common clinical observations, associated with reduced survival and exercise intolerance in patients; making the molecular pathways which regulate these processes of interest. MicroRNAs (miRNAs) are small non-coding RNAs that can reduce mRNA half-life and inhibit protein translation, an...
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ژورنال
عنوان ژورنال: Journal of Thoracic Disease
سال: 2018
ISSN: 2072-1439,2077-6624
DOI: 10.21037/jtd.2018.05.114